node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KQN57138.1 | KQN59148.1 | ASF02_26915 | ASF02_20010 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.966 |
KQN57138.1 | KQN61131.1 | ASF02_26915 | ASF02_12145 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.886 |
KQN57138.1 | KQN61586.1 | ASF02_26915 | ASF02_14550 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | (Fe-S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
KQN57138.1 | KQN61614.1 | ASF02_26915 | ASF02_14705 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
KQN57138.1 | KQN66992.1 | ASF02_26915 | ASF02_05155 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.915 |
KQN57138.1 | acs | ASF02_26915 | ASF02_04115 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.904 |
KQN57138.1 | fadB | ASF02_26915 | ASF02_25285 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.966 |
KQN57138.1 | gltA | ASF02_26915 | ASF02_19630 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.886 |
KQN57138.1 | oadA | ASF02_26915 | ASF02_00770 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
KQN57138.1 | paaZ | ASF02_26915 | ASF02_28015 | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.961 |
KQN59148.1 | KQN57138.1 | ASF02_20010 | ASF02_26915 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
KQN59148.1 | KQN61131.1 | ASF02_20010 | ASF02_12145 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
KQN59148.1 | KQN61586.1 | ASF02_20010 | ASF02_14550 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | (Fe-S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.535 |
KQN59148.1 | KQN61614.1 | ASF02_20010 | ASF02_14705 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
KQN59148.1 | KQN66992.1 | ASF02_20010 | ASF02_05155 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.888 |
KQN59148.1 | acs | ASF02_20010 | ASF02_04115 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.866 |
KQN59148.1 | fadB | ASF02_20010 | ASF02_25285 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.846 |
KQN59148.1 | gltA | ASF02_20010 | ASF02_19630 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.899 |
KQN59148.1 | oadA | ASF02_20010 | ASF02_00770 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
KQN59148.1 | paaZ | ASF02_20010 | ASF02_28015 | 3-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. | enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |