STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQR46568.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)    
Predicted Functional Partners:
KQR44059.1
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
 
 0.988
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
   
  0.893
KQR46980.1
Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.776
KQR43914.1
Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.748
KQR46742.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.724
KQR43708.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.724
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.717
KQR46587.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
    
  0.710
KQR47008.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
    
  0.710
KQR46963.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.684
Your Current Organism:
Frigoribacterium sp. Leaf164
NCBI taxonomy Id: 1736282
Other names: F. sp. Leaf164
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.