close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQP80765.13,4-dihydroxy-2-butanone 4-phosphate synthase; Bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)    
Predicted Functional Partners:
KQP80764.1
6,7-dimethyl-8-ribityllumazine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KQP80766.1
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
KQP80767.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
KQP85088.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.981
KQP82100.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.975
KQP84267.1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.950
ASF35_05290
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.947
KQP82507.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.944
KQP84749.1
Nucleoside diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.935
KQP84334.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.934
Your Current Organism:
Aeromicrobium sp. Leaf291
NCBI taxonomy Id: 1736325
Other names: A. sp. Leaf291
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.