STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnEGlutamine-synthetase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] (998 aa)    
Predicted Functional Partners:
KQQ27578.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
     
 0.903
KQQ27573.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.902
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.734
KQQ27540.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.720
KQQ29031.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.700
KQQ29028.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.694
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.664
KQQ27347.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.638
crgA
Septation inhibitor protein; Involved in cell division; Belongs to the CrgA family.
  
   
 0.633
KQQ27474.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.601
Your Current Organism:
Frondihabitans sp. Leaf304
NCBI taxonomy Id: 1736329
Other names: F. sp. Leaf304
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.