KQQ26817.1 protein (Frondihabitans sp. Leaf304)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

KQQ26817.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)

Predicted Functional Partners:

KQQ26816.1

0.555

KQQ26819.1

0.542

KQQ27006.1

0.512

KQQ26818.1

0.511

KQQ26815.1

0.486

Your Current Organism:

Frondihabitans sp. Leaf304

NCBI taxonomy Id: 1736329
Other names: F. sp. Leaf304

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KQQ26815.1	KQQ26816.1	ASF54_12745	ASF54_12750	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
KQQ26815.1	KQQ26817.1	ASF54_12745	ASF54_12755	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.486
KQQ26815.1	KQQ26819.1	ASF54_12745	ASF54_12765	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.518
KQQ26815.1	KQQ27006.1	ASF54_12745	ASF54_12740	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
KQQ26816.1	KQQ26815.1	ASF54_12750	ASF54_12745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
KQQ26816.1	KQQ26817.1	ASF54_12750	ASF54_12755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
KQQ26816.1	KQQ26818.1	ASF54_12750	ASF54_12760	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.530
KQQ26816.1	KQQ26819.1	ASF54_12750	ASF54_12765	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.578
KQQ26816.1	KQQ27006.1	ASF54_12750	ASF54_12740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.980
KQQ26817.1	KQQ26815.1	ASF54_12755	ASF54_12745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.486
KQQ26817.1	KQQ26816.1	ASF54_12755	ASF54_12750	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
KQQ26817.1	KQQ26818.1	ASF54_12755	ASF54_12760	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
KQQ26817.1	KQQ26819.1	ASF54_12755	ASF54_12765	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
KQQ26817.1	KQQ27006.1	ASF54_12755	ASF54_12740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.512
KQQ26818.1	KQQ26816.1	ASF54_12760	ASF54_12750	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.530
KQQ26818.1	KQQ26817.1	ASF54_12760	ASF54_12755	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
KQQ26818.1	KQQ26819.1	ASF54_12760	ASF54_12765	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.982
KQQ26818.1	KQQ27006.1	ASF54_12760	ASF54_12740	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
KQQ26819.1	KQQ26815.1	ASF54_12765	ASF54_12745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.518
KQQ26819.1	KQQ26816.1	ASF54_12765	ASF54_12750	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.578

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006744

Ubiquinone biosynthetic process

5 of 17

2.0

2.63

2.61e-06

GO:0044249

Cellular biosynthetic process

8 of 722

0.57

0.35

0.0372

GO:1901576

Organic substance biosynthetic process

8 of 740

0.56

0.35

0.0389

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

2 of 2

2.53

0.79

0.0371

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3015

Ubiquinone metabolic process, and BolA protein

7 of 14

2.23

4.98

1.62e-11

CL:3017

Ubiquinone biosynthesis, and Flavoprotein

3 of 5

2.31

2.01

0.00015

CL:1189

Mixed, incl. Fatty acid metabolism, and AMP-binding, conserved site

3 of 44

1.36

0.68

0.0344

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00130

Ubiquinone and other terpenoid-quinone biosynthesis

6 of 70

1.46

1.89

3.16e-06

map01053

Biosynthesis of siderophore group nonribosomal peptides

3 of 35

1.46

0.92

0.0095

map01110

Biosynthesis of secondary metabolites

6 of 472

0.63

0.37

0.0472

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009366

Enterobactin synthetase complex

3 of 5

2.31

1.83

0.00034

GOCC:0110142

Ubiquinone biosynthesis complex

3 of 11

1.96

1.49

0.0011

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0831

Ubiquinone biosynthesis

3 of 6

2.23

1.8

0.00037

KW-0596

Phosphopantetheine

3 of 7

2.16

1.78

0.00037

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00501

AMP-binding enzyme

3 of 8

2.1

1.42

0.0019

PF00668

Condensation domain

2 of 3

2.35

0.88

0.0244

PF13193

AMP-binding enzyme C-terminal domain

2 of 5

2.13

0.79

0.0341

PF00550

Phosphopantetheine attachment site

2 of 6

2.05

0.79

0.0341

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

3 of 3

2.53

1.74

0.00061

IPR036736

ACP-like superfamily

3 of 7

2.16

1.44

0.0018

IPR020845

AMP-binding, conserved site

3 of 7

2.16

1.44

0.0018

IPR009081

Phosphopantetheine binding ACP domain

3 of 7

2.16

1.44

0.0018

IPR045851

AMP-binding enzyme, C-terminal domain superfamily

3 of 8

2.1

1.43

0.0018

(more ...)

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