STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)    
Predicted Functional Partners:
KQT88049.1
Fatty-acid oxidation protein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.915
KQT85904.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.902
KQT85931.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.846
KQT86220.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.846
KQT83394.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.846
KQT83846.1
Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.816
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.809
KQT83463.1
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.777
KQT87485.1
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.699
KQT85969.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.676
Your Current Organism:
Aurantimonas sp. Leaf443
NCBI taxonomy Id: 1736378
Other names: A. sp. Leaf443
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