STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQX52965.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.704
KQX52968.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
KQX52969.1
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family.
  
    0.694
rsfS
Ribosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
     
 0.683
KQX53328.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.622
KQX52966.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.533
KQX47237.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.514
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
  
 0.483
KQX58857.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.429
KQX52722.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.421
Your Current Organism:
Streptomyces sp. Root1304
NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.