STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQX53028.1Translocation protein TolB; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
   
 
  0.682
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
  0.534
KQX53690.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
KQX53479.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
KQX53033.1
Nitrite reductase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.476
KQX53034.1
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
     0.469
KQX47358.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.468
KQX53029.1
Hemoglobin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.459
KQX53030.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.404
Your Current Organism:
Streptomyces sp. Root1304
NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.