STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQX50632.1DNA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (290 aa)    
Predicted Functional Partners:
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
0.928
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.901
KQX52926.1
DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
  
  
 
0.839
KQX50633.1
Diacylglycerol O-acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the long-chain O-acyltransferase family.
       0.835
KQX50634.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.753
KQX51034.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.700
KQX49353.1
Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.679
KQX50636.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
KQX47881.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.635
KQX56115.1
DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family.
  
   
0.593
Your Current Organism:
Streptomyces sp. Root1304
NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304
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