STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQX49891.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)    
Predicted Functional Partners:
KQX46284.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.953
KQX53313.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.945
KQX53420.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.880
KQX57379.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.847
KQX53490.1
TolB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.787
KQX47849.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.742
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.732
KQX57960.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.711
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.703
KQX53338.1
[Fe-S]-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.692
Your Current Organism:
Streptomyces sp. Root1304
NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.