STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQX49405.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)    
Predicted Functional Partners:
KQX54957.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
KQX59197.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.961
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.933
KQX59096.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.932
KQX54956.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.923
KQX53450.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.920
trpE
Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
 
  
 0.919
hisC
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.916
KQX53766.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.916
pat
Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.916
Your Current Organism:
Streptomyces sp. Root1304
NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304
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