nucS protein (Streptomyces sp. Root1304) - STRING interaction network

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Score

nucS

Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (223 aa)

Predicted Functional Partners:

KQX49477.1

0.784

KQX47358.1

0.767

whiB-5

0.745

KQX57511.1

0.738

whiB-4

0.730

whiB-7

0.719

KQX47495.1

0.718

KQX49480.1

0.707

KQX47344.1

0.706

KQX53938.1

0.701

Your Current Organism:

Streptomyces sp. Root1304

NCBI taxonomy Id: 1736450
Other names: S. sp. Root1304

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KQX47344.1	nucS	ASD33_21300	ASD33_21375	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.	0.706
KQX47358.1	nucS	ASD33_21380	ASD33_21375	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.	0.767
KQX47495.1	KQX49477.1	ASD33_22210	ASD33_17195	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.936
KQX47495.1	KQX49480.1	ASD33_22210	ASD33_17210	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	0.406
KQX47495.1	KQX57511.1	ASD33_22210	ASD33_27900	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.429
KQX47495.1	nucS	ASD33_22210	ASD33_21375	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.	0.718
KQX49477.1	KQX47495.1	ASD33_17195	ASD33_22210	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
KQX49477.1	KQX49480.1	ASD33_17195	ASD33_17210	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	0.876
KQX49477.1	KQX57511.1	ASD33_17195	ASD33_27900	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.455
KQX49477.1	nucS	ASD33_17195	ASD33_21375	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.	0.784
KQX49480.1	KQX47495.1	ASD33_17210	ASD33_22210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
KQX49480.1	KQX49477.1	ASD33_17210	ASD33_17195	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.876
KQX49480.1	KQX53938.1	ASD33_17210	ASD33_32775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.606
KQX49480.1	KQX57511.1	ASD33_17210	ASD33_27900	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.697
KQX49480.1	nucS	ASD33_17210	ASD33_21375	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.	0.707
KQX49480.1	whiB-4	ASD33_17210	ASD33_12880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	Transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.594
KQX49480.1	whiB-5	ASD33_17210	ASD33_20645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.655
KQX49480.1	whiB-7	ASD33_17210	ASD33_33090	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.636
KQX53938.1	KQX49480.1	ASD33_32775	ASD33_17210	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.	0.606
KQX53938.1	KQX57511.1	ASD33_32775	ASD33_27900	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.723