STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQZ64023.1Transcriptional regulator; Sigma 54-dependent; regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)    
Predicted Functional Partners:
KQZ64022.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.867
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.849
KQZ64021.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.800
KQZ61481.1
Hypothetical protein; Mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.749
KQZ65623.1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.482
KQZ64019.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.459
KQZ65112.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
Your Current Organism:
Sphingopyxis sp. Root1497
NCBI taxonomy Id: 1736474
Other names: S. sp. Root1497
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.