STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQZ64259.16-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)    
Predicted Functional Partners:
KQZ64199.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
    
   0.941
rpoD
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.941
rpoH
RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
   0.941
KQZ60990.1
DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.864
KQZ64260.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.854
KQZ64258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.849
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 
 0.731
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.651
recA
DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.557
KQZ61213.1
2OG-Fe(II) oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.552
Your Current Organism:
Sphingopyxis sp. Root1497
NCBI taxonomy Id: 1736474
Other names: S. sp. Root1497
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.