STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQZ61502.1Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (379 aa)    
Predicted Functional Partners:
KQZ64447.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.774
lexA
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 0.733
KQZ61503.1
Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.686
KQZ61868.1
GcrA cell cycle regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.611
KQZ64305.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
atpF-2
ATPase; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.538
sucD
succinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.536
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
    0.536
atpF
ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.530
KQZ65816.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.525
Your Current Organism:
Sphingopyxis sp. Root1497
NCBI taxonomy Id: 1736474
Other names: S. sp. Root1497
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.