STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC23355.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transcriptional regulatory Fis family. (77 aa)    
Predicted Functional Partners:
dusB
tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.984
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.864
dusC
tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
  
 0.754
dusA
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
  
  
 0.754
KRC14721.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.737
KRC15034.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
KRC24302.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
KRC21903.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
KRC20971.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
KRC20847.1
PAS domain S-box protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.732
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.