STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC23538.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.960
KRC21983.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.803
KRC23539.1
Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.600
KRC27028.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.548
KRC24388.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.548
KRC29584.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.540
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.517
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.503
KRC20815.1
Acetylpolyamine aminohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.499
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.491
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.