STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBPLP-dependent transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (467 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.910
KRC28088.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.758
KRC28084.1
Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.693
KRC28089.1
Transcriptional regulator; Sigma 54-dependent; regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.690
KRC23306.1
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.606
KRC27413.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.515
KRC27414.1
VWA containing CoxE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
KRC23633.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
   
 0.494
KRC27894.1
ATP-dependent RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
   
 0.494
KRC25163.1
RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
   
 0.494
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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