STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC14656.1PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
ntrC
Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.995
KRC18294.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
0.995
KRC14795.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P(II) protein family.
  
 0.992
KRC22604.1
Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.949
KRC22000.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.926
KRC16836.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.919
KRC23330.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.884
KRC23340.1
Response regulator GlrR; With GlrK is part of a two-component signal transduction system regulating glmY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.883
KRC11733.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.883
KRC23470.1
Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.881
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.