STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC14671.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)    
Predicted Functional Partners:
KRC14670.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.721
KRC18495.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.594
KRC28212.1
General secretion pathway protein GspN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.549
KRC14799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
KRC25692.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.449
KRC29572.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.439
KRC18348.1
Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.435
KRC28213.1
General secretion pathway protein GspJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.403
KRC23969.1
Twin-arginine translocation pathway signal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.400
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.