STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadE-2NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (554 aa)    
Predicted Functional Partners:
KRC16963.1
Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.971
ppnK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.959
cobB
NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
    
 0.945
KRC27348.1
NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.923
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
0.915
KRC24824.1
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.898
KRC27344.1
NADP transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.897
KRC16935.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.878
KRC20799.1
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.826
KRC18247.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
 0.823
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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