STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (317 aa)    
Predicted Functional Partners:
rbsD
Ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
 
 0.985
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.919
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.914
KRC27334.1
Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family.
  
 0.909
KRC27956.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.908
KRC27957.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.879
KRC27959.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.834
KRC27958.1
Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.789
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
 0.754
KRC19185.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.701
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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