| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRC12673.1 | KRC28105.1 | ASE31_11035 | ASE31_15075 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| KRC14996.1 | KRC28105.1 | ASE31_07745 | ASE31_15075 | 16S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| KRC23794.1 | KRC28105.1 | ASE31_04185 | ASE31_15075 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
| KRC23794.1 | folD | ASE31_04185 | ASE31_24260 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.434 |
| KRC23794.1 | gcvT | ASE31_04185 | ASE31_09485 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| KRC23794.1 | glyA | ASE31_04185 | ASE31_08000 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.416 |
| KRC28104.1 | KRC28105.1 | ASE31_15070 | ASE31_15075 | S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
| KRC28104.1 | KRC28106.1 | ASE31_15070 | ASE31_15080 | S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| KRC28105.1 | KRC12673.1 | ASE31_15075 | ASE31_11035 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | 0.430 |
| KRC28105.1 | KRC14996.1 | ASE31_15075 | ASE31_07745 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | 0.430 |
| KRC28105.1 | KRC23794.1 | ASE31_15075 | ASE31_04185 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.410 |
| KRC28105.1 | KRC28104.1 | ASE31_15075 | ASE31_15070 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.615 |
| KRC28105.1 | KRC28106.1 | ASE31_15075 | ASE31_15080 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
| KRC28105.1 | dut | ASE31_15075 | ASE31_04600 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.428 |
| KRC28105.1 | folD | ASE31_15075 | ASE31_24260 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.410 |
| KRC28105.1 | gcvT | ASE31_15075 | ASE31_09485 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| KRC28105.1 | glyA | ASE31_15075 | ASE31_08000 | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.417 |
| KRC28106.1 | KRC28104.1 | ASE31_15080 | ASE31_15070 | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. | S26 family signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.438 |
| KRC28106.1 | KRC28105.1 | ASE31_15080 | ASE31_15075 | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
| dut | KRC28105.1 | ASE31_04600 | ASE31_15075 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 23S rRNA methyltransferase; SAM-dependent;catalyzes the methylation of cytosine at position 1962 of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |