STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC27094.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.806
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.806
KRC14750.1
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.790
KRC27304.1
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.679
KRC27207.1
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.672
KRC23557.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.668
KRC20864.1
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.665
KRC28005.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.664
KRC27096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.640
KRC27204.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.607
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.