STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuNon-homologous end joining protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (319 aa)    
Predicted Functional Partners:
KRC24866.1
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.931
ligD
ATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.931
KRC26075.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.603
KRC12973.1
DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.565
KRC26951.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.558
KRC27065.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.443
KRC23165.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.414
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.