STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRC24821.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)    
Predicted Functional Partners:
KRC17472.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.510
fliM
Flagellar motor switch protein FliM; With FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.507
KRC17613.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.448
KRC25687.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.433
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.427
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.423
KRC24820.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.408
KRC18240.1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.404
Your Current Organism:
Acidovorax sp. Root217
NCBI taxonomy Id: 1736492
Other names: A. sp. Root217
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.