OCC06759.1 protein (Labrys sp. WJW) - STRING interaction network

Nodes:

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

OCC06759.1

acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)

Predicted Functional Partners:

OCC05362.1

0.970

OCC00396.1

0.943

OCC05363.1

0.867

OCC01231.1

0.851

OCC02086.1

0.849

OCC07058.1

0.840

OCC06757.1

0.810

OCC06762.1

0.786

OCC04906.1

0.778

OCC06758.1

0.768

Your Current Organism:

Labrys sp. WJW

NCBI taxonomy Id: 1737983
Other names: L. sp. WJW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OCC00396.1	OCC01231.1	BA190_34250	BA190_30095	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.877
OCC00396.1	OCC02086.1	BA190_34250	BA190_25450	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
OCC00396.1	OCC04906.1	BA190_34250	BA190_10910	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.753
OCC00396.1	OCC05362.1	BA190_34250	BA190_07960	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.901
OCC00396.1	OCC05363.1	BA190_34250	BA190_07965	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
OCC00396.1	OCC06759.1	BA190_34250	BA190_00560	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.943
OCC00396.1	OCC06762.1	BA190_34250	BA190_00575	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.750
OCC00396.1	OCC07058.1	BA190_34250	BA190_00555	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.532
OCC01231.1	OCC00396.1	BA190_30095	BA190_34250	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.877
OCC01231.1	OCC02086.1	BA190_30095	BA190_25450	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OCC01231.1	OCC05362.1	BA190_30095	BA190_07960	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.667
OCC01231.1	OCC05363.1	BA190_30095	BA190_07965	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.625
OCC01231.1	OCC06759.1	BA190_30095	BA190_00560	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.851
OCC02086.1	OCC00396.1	BA190_25450	BA190_34250	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
OCC02086.1	OCC01231.1	BA190_25450	BA190_30095	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OCC02086.1	OCC04906.1	BA190_25450	BA190_10910	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
OCC02086.1	OCC05362.1	BA190_25450	BA190_07960	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.636
OCC02086.1	OCC05363.1	BA190_25450	BA190_07965	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.522
OCC02086.1	OCC06759.1	BA190_25450	BA190_00560	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.849
OCC02086.1	OCC06762.1	BA190_25450	BA190_00575	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988

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Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.595

expected number of edges:

12

PPI enrichment p-value:

7.32e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901678

Iron coordination entity transport

3 of 14

1.87

0.93

0.0162

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022857

Transmembrane transporter activity

7 of 387

0.8

0.5

0.0205

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030312

External encapsulating structure

5 of 71

1.39

0.00017

GO:0009279

Cell outer membrane

4 of 44

1.5

1.37

0.00051

GO:0031224

Intrinsic component of membrane

9 of 789

0.59

0.48

0.0010

GO:0071944

Cell periphery

8 of 726

0.58

0.44

0.0037

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5000

Protein transport, and TonB-dependent Receptor Plug Domain

6 of 31

1.82

2.8

2.13e-07

CL:5002

Mixed, incl. Biopolymer transport protein ExbD/TolR, and Transmembrane beta strand

5 of 19

1.96

2.75

1.03e-06

CL:5003

Biopolymer transport protein ExbD/TolR, and MotA/TolQ/ExbB proton channel

3 of 13

1.9

1.43

0.0014

CL:5028

Transmembrane beta strand

2 of 6

2.06

0.85

0.0260

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030312

External encapsulating structure

5 of 57

1.48

1.54

0.00012

GOCC:0009279

Cell outer membrane

3 of 40

1.41

0.71

0.0301

GOCC:0071944

Cell periphery

7 of 554

0.64

0.4

0.0301

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0798

TonB box

3 of 10

2.01

1.51

0.0011

KW-0675

Receptor

3 of 14

1.87

1.43

0.0013

KW-0998

Cell outer membrane

3 of 18

1.76

1.33

0.0017

KW-1134

Transmembrane beta strand

2 of 8

1.94

0.9

0.0190

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07715

TonB-dependent Receptor Plug Domain

4 of 11

2.1

2.26

2.93e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039426

TonB-dependent receptor-like

4 of 10

2.14

2.16

5.60e-05

IPR037066

TonB-dependent receptor, plug domain superfamily

4 of 11

2.1

2.14

5.60e-05

IPR012910

TonB-dependent receptor, plug domain

4 of 11

2.1

2.14

5.60e-05

IPR036942

TonB-dependent receptor-like, beta-barrel domain superfamily

3 of 10

2.01

1.4

0.0019

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