OCC03860.1 protein (Labrys sp. WJW) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OCC03860.1

Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)

Predicted Functional Partners:

OCC03761.1

0.999

OCC04954.1

0.994

OCC01801.1

0.994

OCC06252.1

0.991

OCC01957.1

0.991

OCC01951.1

0.990

OCC01936.1

0.989

OCC01947.1

0.982

OCC05170.1

0.981

OCC03760.1

0.981

Your Current Organism:

Labrys sp. WJW

NCBI taxonomy Id: 1737983
Other names: L. sp. WJW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OCC01801.1	OCC01936.1	BA190_26670	BA190_26460	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OCC01801.1	OCC01947.1	BA190_26670	BA190_26525	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
OCC01801.1	OCC01951.1	BA190_26670	BA190_26545	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
OCC01801.1	OCC01957.1	BA190_26670	BA190_26490	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OCC01801.1	OCC03760.1	BA190_26670	BA190_16880	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OCC01801.1	OCC03761.1	BA190_26670	BA190_16885	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
OCC01801.1	OCC03860.1	BA190_26670	BA190_16570	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
OCC01801.1	OCC04954.1	BA190_26670	BA190_11215	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OCC01801.1	OCC05170.1	BA190_26670	BA190_09660	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.894
OCC01801.1	OCC06252.1	BA190_26670	BA190_04425	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.865
OCC01936.1	OCC01801.1	BA190_26460	BA190_26670	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
OCC01936.1	OCC01947.1	BA190_26460	BA190_26525	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
OCC01936.1	OCC01951.1	BA190_26460	BA190_26545	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
OCC01936.1	OCC01957.1	BA190_26460	BA190_26490	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OCC01936.1	OCC03760.1	BA190_26460	BA190_16880	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
OCC01936.1	OCC03761.1	BA190_26460	BA190_16885	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
OCC01936.1	OCC03860.1	BA190_26460	BA190_16570	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
OCC01936.1	OCC04954.1	BA190_26460	BA190_11215	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
OCC01936.1	OCC05170.1	BA190_26460	BA190_09660	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
OCC01936.1	OCC06252.1	BA190_26460	BA190_04425	Phosphoribosylformylglycinamidine synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.836

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Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.849

expected number of edges:

12

PPI enrichment p-value:

7.06e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009089

Lysine biosynthetic process via diaminopimelate

5 of 13

2.08

3.2

1.53e-07

GO:1901607

Alpha-amino acid biosynthetic process

9 of 95

1.47

2.55

5.01e-10

GO:1901605

Alpha-amino acid metabolic process

10 of 125

1.4

2.41

8.55e-11

GO:0006526

Arginine biosynthetic process

4 of 13

1.98

2.4

9.23e-06

GO:0019877

Diaminopimelate biosynthetic process

2 of 9

1.84

0.87

0.0210

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030170

Pyridoxal phosphate binding

4 of 29

1.63

1.3

0.0015

GO:0008483

Transaminase activity

3 of 18

1.71

1.11

0.0054

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1103

Lysine biosynthesis, and Arginine biosynthesis

10 of 18

2.24

7.4

1.84e-18

CL:1105

Lysine biosynthesis, and Peptidase family M20/M25/M40

4 of 8

2.19

2.69

4.38e-06

CL:1124

Arginine biosynthesis

3 of 5

2.27

1.96

0.00018

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00300

Lysine biosynthesis

7 of 22

1.99

4.36

2.92e-11

map00220

Arginine biosynthesis

5 of 21

1.87

2.82

3.18e-07

map01230

Biosynthesis of amino acids

11 of 145

1.37

2.57

1.56e-13

map01210

2-Oxocarboxylic acid metabolism

4 of 27

1.66

1.82

5.50e-05

map01110

Biosynthesis of secondary metabolites

8 of 508

0.69

0.57

0.00069

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

4 of 9

2.14

2.65

4.34e-06

KW-0028

Amino-acid biosynthesis

7 of 63

1.54

2.37

7.25e-08

KW-0457

Lysine biosynthesis

3 of 6

2.19

1.97

0.00015

KW-0032

Aminotransferase

3 of 13

1.86

1.53

0.00072

KW-0963

Cytoplasm

6 of 226

0.92

0.75

0.0013

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