OCC02262.1 protein (Labrys sp. WJW) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

OCC02262.1

Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)

Predicted Functional Partners:

OCC02261.1

0.806

OCC02260.1

0.768

OCC02263.1

0.759

OCC03322.1

0.723

OCC02668.1

0.708

OCC06647.1

0.707

OCC07042.1

0.688

OCC03183.1

0.679

OCC04514.1

0.676

OCC04718.1

0.676

Your Current Organism:

Labrys sp. WJW

NCBI taxonomy Id: 1737983
Other names: L. sp. WJW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OCC02260.1	OCC02261.1	BA190_24735	BA190_24740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.768
OCC02260.1	OCC02262.1	BA190_24735	BA190_24745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.768
OCC02260.1	OCC02263.1	BA190_24735	BA190_24750	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.410
OCC02261.1	OCC02260.1	BA190_24740	BA190_24735	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.768
OCC02261.1	OCC02262.1	BA190_24740	BA190_24745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.806
OCC02261.1	OCC02263.1	BA190_24740	BA190_24750	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.562
OCC02262.1	OCC02260.1	BA190_24745	BA190_24735	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.768
OCC02262.1	OCC02261.1	BA190_24745	BA190_24740	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.806
OCC02262.1	OCC02263.1	BA190_24745	BA190_24750	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.759
OCC02262.1	OCC02668.1	BA190_24745	BA190_23195	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Xylulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.708
OCC02262.1	OCC03183.1	BA190_24745	BA190_19550	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.679
OCC02262.1	OCC03322.1	BA190_24745	BA190_19190	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Xylulose kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.723
OCC02262.1	OCC04514.1	BA190_24745	BA190_12425	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	L-threonine 3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
OCC02262.1	OCC04718.1	BA190_24745	BA190_12975	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
OCC02262.1	OCC06647.1	BA190_24745	BA190_02335	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Xylulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.707
OCC02262.1	OCC07042.1	BA190_24745	BA190_02150	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.688
OCC02263.1	OCC02260.1	BA190_24750	BA190_24735	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.410
OCC02263.1	OCC02261.1	BA190_24750	BA190_24740	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.562
OCC02263.1	OCC02262.1	BA190_24750	BA190_24745	SgcQ protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.759
OCC02668.1	OCC02262.1	BA190_23195	BA190_24745	Xylulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.708

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

22

PPI enrichment p-value:

9.46e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 94

1.44

2.8

2.73e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 48

1.64

3.33

1.75e-11

GO:0019843

rRNA binding

6 of 40

1.55

2.09

1.68e-06

GO:0003723

RNA binding

7 of 94

1.24

1.49

4.21e-06

GO:0000049

tRNA binding

3 of 23

1.49

0.93

0.0091

GO:0003676

Nucleic acid binding

9 of 273

0.89

0.9

8.99e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044391

Ribosomal subunit

6 of 12

2.07

4.15

3.99e-10

GO:0005840

Ribosome

9 of 52

1.61

3.27

7.67e-12

GO:0015935

Small ribosomal subunit

3 of 5

2.15

2.24

3.79e-05

GO:0015934

Large ribosomal subunit

3 of 7

2.0

2.04

7.24e-05

GO:0005622

Intracellular anatomical structure

11 of 764

0.53

0.47

2.44e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1226

Ribosome

10 of 60

1.59

3.36

6.61e-13

CL:1231

Ribosome

9 of 55

1.58

3.21

4.85e-12

CL:1232

Ribosomal protein

6 of 29

1.69

2.73

4.86e-08

CL:1210

Translation, and Protein export

11 of 131

1.29

2.22

1.34e-12

CL:1279

Small ribosomal subunit, and Ribosomal protein

3 of 5

2.15

2.07

8.52e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 52

1.61

3.28

6.82e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 35

1.67

2.85

1.08e-08

GOCC:0044391

Ribosomal subunit

4 of 15

1.8

2.09

2.16e-05

GOCC:0022626

Cytosolic ribosome

3 of 11

1.81

1.6

0.00044

GOCC:0043229

Intracellular organelle

9 of 215

0.99

1.11

1.08e-06

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

1.83

0.99

0.0113

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

8 of 48

1.59

2.88

7.50e-10

KW-0699

rRNA-binding

6 of 39

1.56

2.24

4.70e-07

KW-0820

tRNA-binding

2 of 11

1.63

0.7

0.0415

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