STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH59932.1tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. (156 aa)    
Predicted Functional Partners:
SEH99019.1
Acetyltransferase (GNAT) family protein.
  
 0.996
SEH78818.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
 
 0.994
tsaD
N6-L-threonylcarbamoyladenine synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.989
SEI05603.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.914
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
   
 0.891
SEH59949.1
N-acetylmuramoyl-L-alanine amidase.
  
 
 0.890
nnrD
yjeF C-terminal region, hydroxyethylthiazole kinase-related; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
 
 
 0.862
SEI03113.1
tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Belongs to the SUA5 family.
    
 0.860
SEH60209.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.850
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.843
Your Current Organism:
Rheinheimera pacifica
NCBI taxonomy Id: 173990
Other names: CCUG 46544, DSM 17616, IAM 15043, JCM 12090, NBRC 103167, NRIC 0539, R. pacifica, Rheinheimera pacifica Romanenko et al. 2003
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