STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH75334.1hydroxymethylglutaryl-CoA lyase. (304 aa)    
Predicted Functional Partners:
SEH75303.1
methylglutaconyl-CoA hydratase.
 
 0.998
SEH75287.1
3-methylcrotonyl-CoA carboxylase beta subunit.
 0.985
SEI05611.1
Acyl transferase domain-containing protein.
  
 
 0.962
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.955
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.953
SEI05603.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.941
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.939
SEH75195.1
Enoyl-CoA hydratase/isomerase.
  
 
 0.939
SEI06465.1
Isocitrate dehydrogenase (NAD+).
  
 0.939
SEI05128.1
Acetolactate synthase, small subunit.
  
 
 0.928
Your Current Organism:
Rheinheimera pacifica
NCBI taxonomy Id: 173990
Other names: CCUG 46544, DSM 17616, IAM 15043, JCM 12090, NBRC 103167, NRIC 0539, R. pacifica, Rheinheimera pacifica Romanenko et al. 2003
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