STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH95290.1Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (588 aa)    
Predicted Functional Partners:
SEH95269.1
CBS domain-containing protein.
 
  
 0.983
SEH95302.1
Putative solute:sodium symporter small subunit.
 
    0.966
SEH95281.1
Hypothetical protein.
 
     0.899
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.818
SEH92100.1
propionyl-CoA synthetase.
  
  
 0.808
SEH95256.1
DNA polymerase-3 subunit epsilon.
 
    0.785
SEH66079.1
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase.
  
  
 0.761
SEH95315.1
Na+/proline symporter.
     
 0.730
fadJ
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.643
fadB
Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.643
Your Current Organism:
Rheinheimera pacifica
NCBI taxonomy Id: 173990
Other names: CCUG 46544, DSM 17616, IAM 15043, JCM 12090, NBRC 103167, NRIC 0539, R. pacifica, Rheinheimera pacifica Romanenko et al. 2003
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