STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpAUnannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)    
Predicted Functional Partners:
trpB
Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpF
Unannotated protein; Belongs to the TrpF family.
 
 
 0.999
trpC
Unannotated protein; Belongs to the TrpC family.
 
 
 0.999
trpD
Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.999
E0Y62_19630
Unannotated protein.
 
 
 0.995
trpE
Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
 
  
 0.990
pabA
Unannotated protein.
 
 
 0.980
E0Y62_18175
Unannotated protein.
 
  
 0.958
E0Y62_08320
Unannotated protein.
   
 
 0.879
lgt
Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.858
Your Current Organism:
Bacillus praedii
NCBI taxonomy Id: 1742358
Other names: B. praedii, Bacillus praedii Liu et al. 2017, Bacillus sp. FJAT-25547, CCTCC AB 2015208, DSM 101002, strain FJAT-25547
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.