node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A2J6PFC6 | A0A2J6PQV8 | A0A2J6PFC6 | A0A2J6PQV8 | Zinc/iron permease. | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | 0.497 |
A0A2J6PFC6 | MDM34 | A0A2J6PFC6 | A0A2J6Q480 | Zinc/iron permease. | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. | 0.497 |
A0A2J6PFC6 | MMM1 | A0A2J6PFC6 | A0A2J6PLU4 | Zinc/iron permease. | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] | 0.701 |
A0A2J6PP30 | A0A2J6PQV8 | A0A2J6PP30 | A0A2J6PQV8 | Uncharacterized protein. | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | 0.497 |
A0A2J6PP30 | MDM34 | A0A2J6PP30 | A0A2J6Q480 | Uncharacterized protein. | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. | 0.497 |
A0A2J6PP30 | MMM1 | A0A2J6PP30 | A0A2J6PLU4 | Uncharacterized protein. | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] | 0.701 |
A0A2J6PQV8 | A0A2J6PFC6 | A0A2J6PQV8 | A0A2J6PFC6 | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | Zinc/iron permease. | 0.497 |
A0A2J6PQV8 | A0A2J6PP30 | A0A2J6PQV8 | A0A2J6PP30 | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.497 |
A0A2J6PQV8 | A0A2J6PVH6 | A0A2J6PQV8 | A0A2J6PVH6 | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | High affinity zinc ion transporter. | 0.497 |
A0A2J6PQV8 | MDM10 | A0A2J6PQV8 | A0A2J6Q6F7 | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] | 0.497 |
A0A2J6PQV8 | MMM1 | A0A2J6PQV8 | A0A2J6PLU4 | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] | 0.875 |
A0A2J6PVH6 | A0A2J6PQV8 | A0A2J6PVH6 | A0A2J6PQV8 | High affinity zinc ion transporter. | Casein kinase II, alpha chain; Belongs to the protein kinase superfamily. | 0.497 |
A0A2J6PVH6 | MDM34 | A0A2J6PVH6 | A0A2J6Q480 | High affinity zinc ion transporter. | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. | 0.497 |
A0A2J6PVH6 | MMM1 | A0A2J6PVH6 | A0A2J6PLU4 | High affinity zinc ion transporter. | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] | 0.701 |
A0A2J6PZ91 | A0A2J6QK09 | A0A2J6PZ91 | A0A2J6QK09 | Uncharacterized protein. | Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.725 |
A0A2J6PZ91 | MDM10 | A0A2J6PZ91 | A0A2J6Q6F7 | Uncharacterized protein. | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] | 0.882 |
A0A2J6PZ91 | MDM34 | A0A2J6PZ91 | A0A2J6Q480 | Uncharacterized protein. | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. | 0.808 |
A0A2J6PZ91 | MMM1 | A0A2J6PZ91 | A0A2J6PLU4 | Uncharacterized protein. | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] | 0.899 |
A0A2J6Q4C6 | A0A2J6QK09 | A0A2J6Q4C6 | A0A2J6QK09 | Protein kinase domain-containing protein. | Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.725 |
A0A2J6Q4C6 | MDM10 | A0A2J6Q4C6 | A0A2J6Q6F7 | Protein kinase domain-containing protein. | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] | 0.882 |