A0A2J6Q5H5 protein (Pezoloma ericae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A2J6Q5H5

Uncharacterized protein. (809 aa)

Predicted Functional Partners:

A0A2J6PXD9

0.998

A0A2J6PM79

0.997

A0A2J6PEU3

0.970

A0A2J6Q6N3

0.965

LSM1

0.943

A0A2J6QC58

0.943

A0A2J6PL75

0.942

A0A2J6PYJ5

0.942

A0A2J6Q7R3

0.942

A0A2J6Q6P3

0.937

Your Current Organism:

Pezoloma ericae

NCBI taxonomy Id: 1745343
Other names: Hymenoscyphus ericae, P. ericae, Pezizella ericae, Pezizella ericae D.J.Read, Pezoloma ericae (D.J. Read) Baral, 2006, Rhizoscyphus ericae, UAMH 6735

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2J6PEU3	A0A2J6PM79	A0A2J6PEU3	A0A2J6PM79	Sm domain-containing protein.	PH domain-like protein.	0.836
A0A2J6PEU3	A0A2J6PYJ5	A0A2J6PEU3	A0A2J6PYJ5	Sm domain-containing protein.	PAT1 domain-containing protein.	0.972
A0A2J6PEU3	A0A2J6Q5H5	A0A2J6PEU3	A0A2J6Q5H5	Sm domain-containing protein.	Uncharacterized protein.	0.970
A0A2J6PEU3	A0A2J6Q6N3	A0A2J6PEU3	A0A2J6Q6N3	Sm domain-containing protein.	Uncharacterized protein.	0.840
A0A2J6PEU3	A0A2J6Q6P3	A0A2J6PEU3	A0A2J6Q6P3	Sm domain-containing protein.	Nudix hydrolase domain-containing protein.	0.823
A0A2J6PEU3	A0A2J6Q7R3	A0A2J6PEU3	A0A2J6Q7R3	Sm domain-containing protein.	PAT1 domain-containing protein.	0.972
A0A2J6PEU3	A0A2J6QC58	A0A2J6PEU3	A0A2J6QC58	Sm domain-containing protein.	Uncharacterized protein.	0.982
A0A2J6PEU3	LSM1	A0A2J6PEU3	A0A2J6QC26	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.982
A0A2J6PL75	A0A2J6Q5H5	A0A2J6PL75	A0A2J6Q5H5	Centromere/microtubule-binding protein cbf5.	Uncharacterized protein.	0.942
A0A2J6PM79	A0A2J6PEU3	A0A2J6PM79	A0A2J6PEU3	PH domain-like protein.	Sm domain-containing protein.	0.836
A0A2J6PM79	A0A2J6PXD9	A0A2J6PM79	A0A2J6PXD9	PH domain-like protein.	CCHC-type domain-containing protein.	0.485
A0A2J6PM79	A0A2J6PYJ5	A0A2J6PM79	A0A2J6PYJ5	PH domain-like protein.	PAT1 domain-containing protein.	0.959
A0A2J6PM79	A0A2J6Q5H5	A0A2J6PM79	A0A2J6Q5H5	PH domain-like protein.	Uncharacterized protein.	0.997
A0A2J6PM79	A0A2J6Q6N3	A0A2J6PM79	A0A2J6Q6N3	PH domain-like protein.	Uncharacterized protein.	0.977
A0A2J6PM79	A0A2J6Q6P3	A0A2J6PM79	A0A2J6Q6P3	PH domain-like protein.	Nudix hydrolase domain-containing protein.	0.977
A0A2J6PM79	A0A2J6Q7R3	A0A2J6PM79	A0A2J6Q7R3	PH domain-like protein.	PAT1 domain-containing protein.	0.959
A0A2J6PM79	A0A2J6QC58	A0A2J6PM79	A0A2J6QC58	PH domain-like protein.	Uncharacterized protein.	0.787
A0A2J6PM79	LSM1	A0A2J6PM79	A0A2J6QC26	PH domain-like protein.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.787
A0A2J6PXD9	A0A2J6PM79	A0A2J6PXD9	A0A2J6PM79	CCHC-type domain-containing protein.	PH domain-like protein.	0.485
A0A2J6PXD9	A0A2J6Q5H5	A0A2J6PXD9	A0A2J6Q5H5	CCHC-type domain-containing protein.	Uncharacterized protein.	0.998

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

17

PPI enrichment p-value:

1.3e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

8 of 103

1.36

1.89

2.66e-07

GO:0010467

Gene expression

9 of 196

1.13

1.42

2.66e-07

GO:0044260

Cellular macromolecule metabolic process

9 of 375

0.85

0.82

2.47e-05

GO:0034641

Cellular nitrogen compound metabolic process

9 of 663

0.6

0.47

0.0021

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

8 of 53

1.65

3.02

1.01e-09

GO:0019843

rRNA binding

6 of 42

1.62

2.32

7.31e-07

GO:0003723

RNA binding

7 of 93

1.35

1.77

1.05e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

8 of 56

1.62

3.06

2.70e-10

GO:0015934

Large ribosomal subunit

2 of 8

1.87

1.07

0.0079

GO:0005622

Intracellular anatomical structure

10 of 1083

0.44

0.35

0.0027

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:145

Structural constituent of ribosome

8 of 34

1.84

3.88

4.36e-11

CL:146

Structural constituent of ribosome

7 of 29

1.85

3.66

4.16e-10

CL:150

rRNA-binding

4 of 10

2.07

2.72

2.26e-06

CL:147

rRNA-binding

5 of 23

1.81

2.66

4.91e-07

CL:124

Ribosome, and Regulation of translation

9 of 107

1.39

2.34

4.16e-10

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 56

1.62

3.06

2.77e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

6 of 39

1.66

2.39

6.54e-07

GOCC:0015934

Large ribosomal subunit

3 of 7

2.1

1.92

0.00017

GOCC:0043232

Intracellular non-membrane-bounded organelle

7 of 126

1.21

1.42

7.05e-06

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 4

2.17

1.21

0.0052

GOCC:0043229

Intracellular organelle

8 of 330

0.85

0.78

0.00012

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

8 of 56

1.62

3.02

4.57e-10

KW-0699

rRNA-binding

6 of 39

1.66

2.55

1.47e-07

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