STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2J6Q852Uncharacterized protein. (182 aa)    
Predicted Functional Partners:
A0A2J6PJC7
Uncharacterized protein.
  
 0.900
A0A2J6QCY2
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.882
A0A2J6PRI5
RMI1_N domain-containing protein.
    
 0.863
A0A2J6Q959
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.836
A0A2J6Q1B7
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.833
A0A2J6QM87
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.830
A0A2J6QET4
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.828
A0A2J6PGA3
Protein kinase-like protein rad3; Belongs to the PI3/PI4-kinase family.
   
 0.823
A0A2J6QN99
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.815
A0A2J6QND5
MUS38-like protein.
    
 0.811
Your Current Organism:
Pezoloma ericae
NCBI taxonomy Id: 1745343
Other names: Hymenoscyphus ericae, P. ericae, Pezizella ericae, Pezizella ericae D.J.Read, Pezoloma ericae (D.J. Read) Baral, 2006, Rhizoscyphus ericae, UAMH 6735
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