Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ALT34789.1Repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)    
Predicted Functional Partners:
ALT35834.1
Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.760
ALT36380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.743
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
      
 0.534
ALT34790.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
     
 0.534
ALT34788.1
N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.533
ALT36452.1
Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
  
 0.533
ALT34632.1
Glutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.532
ALT34787.1
Phosphoserine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.528
tpx
Peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.515
ALT34981.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.505
Your Current Organism:
Cutibacterium acnes
NCBI taxonomy Id: 1747
Other names: ATCC 6919, Bacillus acnes, C. acnes, CIP 53.117, Corynebacterium acnes, DSM 16379, JCM 6425, LMG 16711, LMG:16711, NCTC 737, NRRL B-4224, Propionibacterium acnes, Propionicibacterium acnes
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