STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)    
Predicted Functional Partners:
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
 
 
 0.990
ALT36466.1
1-deoxy-D-xylulose-5-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
ALT35639.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.960
ALT35636.1
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
 
  
 0.942
ALT36365.1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.903
ALT34863.1
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.897
ALT34822.1
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.893
ALT36451.1
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.880
ALT34857.1
UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.821
ALT35647.1
Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family.
  
  
 0.762
Your Current Organism:
Cutibacterium acnes
NCBI taxonomy Id: 1747
Other names: ATCC 6919, Bacillus acnes, C. acnes, CIP 53.117, Corynebacterium acnes, DSM 16379, JCM 6425, LMG 16711, LMG:16711, NCTC 737, NRRL B-4224, Propionibacterium acnes, Propionicibacterium acnes
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.