STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1169 aa)    
Predicted Functional Partners:
Tel_09740
Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.949
zipA
Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
  
 0.750
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
       0.648
Tel_10230
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Needed for nucleoid integrity; possibly involved in cell wall synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.645
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.625
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.601
Tel_14540
Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family.
 
 
 0.550
Tel_10250
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.506
cysZ
Sulfate transporter; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.
       0.460
Tel_10225
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.458
Your Current Organism:
Tenderia electrophaga
NCBI taxonomy Id: 1748243
Other names: C. Tenderia electrophaga, Candidatus Tenderia electrophaga, Gammaproteobacteria bacterium NRL1
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