STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipA-2Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (308 aa)    
Predicted Functional Partners:
lipB
Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.997
BAU14069.1
Biotin/lipoate A/B protein ligase; Similar to AA sequence:cyanobase_aa:LBDG_51050.
 
 
 0.936
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
  
 
0.906
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.840
BAU14252.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; Similar to AA sequence:cyanobase_aa:LBDG_06640.
 
  
 0.618
BAU12661.1
Pyridine nucleotide-disulphide oxidoreductase dimerisation region; Similar to AA sequence:cyanobase_aa:LBDG_18650.
 
  
 0.511
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.497
BAU15153.1
Dihydrolipoamide dehydrogenase; Similar to AA sequence:cyanobase_aa:LBDG_30110.
 
  
 0.482
BAU13531.1
Glutathione-disulfide reductase; Similar to AA sequence:cyanobase_aa:LBDG_27970.
 
  
 0.461
BAU13622.1
Response regulator receiver protein; Similar to AA sequence:cyanobase_aa:LBDG_03120.
       0.453
Your Current Organism:
Leptolyngbya sp. NIES3755
NCBI taxonomy Id: 1752064
Other names: L. sp. NIES-3755, Leptolyngbya sp. NIES-3755
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