STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2CD59AAA-ATPase_like domain-containing protein. (177 aa)    
Predicted Functional Partners:
A0A1Y2F057
Rhodanese domain-containing protein.
  
 
 0.550
A0A1Y2F464
Rhodanese-like protein.
  
 
 0.550
A0A1Y2BFZ4
Ubiquitin-activating emzyme E1; Belongs to the ubiquitin-activating E1 family.
  
 
 0.522
A0A1Y2BNC5
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
  
 
 0.522
A0A1Y2BRD7
SUMO-1 activating enzyme subunit 1, isoform CRA_b.
  
 
 0.522
A0A1Y2DMH4
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
  
 
 0.522
A0A1Y2DU06
Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family.
  
 
 0.522
A0A1Y2EXG2
E2_bind domain-containing protein.
  
 
 0.522
A0A1Y2BZE5
Seryl-tRNA synthetase.
   
  0.469
A0A1Y2ESA9
Serine-tRNA ligase.
   
  0.469
Your Current Organism:
Neocallimastix californiae
NCBI taxonomy Id: 1754190
Other names: G1, JMRC:SF:12176, N. californiae, Neocallimastix sp. G1, Neocallimastix sp. KS-2015
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.