A0A1Y1VR49 protein (Anaeromyces robustus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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[Homology]

Score

A0A1Y1VR49

Kinase-like protein. (1545 aa)

Predicted Functional Partners:

A0A1Y1X178

0.936

A0A1Y1XN25

0.895

A0A1Y1VQQ2

0.835

A0A1Y1X860

0.741

A0A1Y1XLR2

0.741

A0A1Y1XDS7

0.739

A0A1Y1XN90

0.715

A0A1Y1XHN6

0.711

A0A1Y1X8T2

0.695

A0A1Y1XC34

0.692

Your Current Organism:

Anaeromyces robustus

NCBI taxonomy Id: 1754192
Other names: A. robustus, Anaeromyces sp. KS-2015, Anaeromyces sp. S4, JMRC:SF:12178, S4

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y1VQQ2	A0A1Y1VR49	PRA-CH domain-containing protein.	Kinase-like protein.	0.835
A0A1Y1VQQ2	A0A1Y1X178	PRA-CH domain-containing protein.	S1 motif domain-containing protein.	0.474
A0A1Y1VQQ2	A0A1Y1X860	PRA-CH domain-containing protein.	Serine/threonine-protein kinase.	0.835
A0A1Y1VQQ2	A0A1Y1XDS7	PRA-CH domain-containing protein.	Tr-type G domain-containing protein.	0.489
A0A1Y1VQQ2	A0A1Y1XN25	PRA-CH domain-containing protein.	HisG-domain-containing protein.	0.996
A0A1Y1VQQ2	A0A1Y1XN90	PRA-CH domain-containing protein.	Histidyl-tRNA synthetase.	0.835
A0A1Y1VR49	A0A1Y1VQQ2	Kinase-like protein.	PRA-CH domain-containing protein.	0.835
A0A1Y1VR49	A0A1Y1X178	Kinase-like protein.	S1 motif domain-containing protein.	0.936
A0A1Y1VR49	A0A1Y1X860	Kinase-like protein.	Serine/threonine-protein kinase.	0.741
A0A1Y1VR49	A0A1Y1X8T2	Kinase-like protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.695
A0A1Y1VR49	A0A1Y1XC34	Kinase-like protein.	Tyrosine--tRNA ligase.	0.692
A0A1Y1VR49	A0A1Y1XDS7	Kinase-like protein.	Tr-type G domain-containing protein.	0.739
A0A1Y1VR49	A0A1Y1XHN6	Kinase-like protein.	WD_REPEATS_REGION domain-containing protein.	0.711
A0A1Y1VR49	A0A1Y1XLR2	Kinase-like protein.	Kinase-like protein.	0.741
A0A1Y1VR49	A0A1Y1XN25	Kinase-like protein.	HisG-domain-containing protein.	0.895
A0A1Y1VR49	A0A1Y1XN90	Kinase-like protein.	Histidyl-tRNA synthetase.	0.715
A0A1Y1X178	A0A1Y1VQQ2	S1 motif domain-containing protein.	PRA-CH domain-containing protein.	0.474
A0A1Y1X178	A0A1Y1VR49	S1 motif domain-containing protein.	Kinase-like protein.	0.936
A0A1Y1X178	A0A1Y1X860	S1 motif domain-containing protein.	Serine/threonine-protein kinase.	0.952
A0A1Y1X178	A0A1Y1X8T2	S1 motif domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.838

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

19

average node degree:

3.45

avg. local clustering coefficient:

0.782

expected number of edges:

22

PPI enrichment p-value:

0.778

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0018106

Peptidyl-histidine phosphorylation

6 of 58

1.72

2.5

5.81e-07

GO:0000160

Phosphorelay signal transduction system

6 of 94

1.51

1.98

3.00e-06

GO:0016310

Phosphorylation

7 of 189

1.27

1.56

3.64e-06

GO:0050896

Response to stimulus

10 of 452

1.05

1.26

2.06e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004673

Protein histidine kinase activity

7 of 62

1.76

3.08

8.78e-09

GO:0000155

Phosphorelay sensor kinase activity

3 of 35

1.64

1.09

0.0050

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3899

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain, and Signal transduction response regulator, receiver domain

7 of 19

2.27

5.41

2.04e-12

CL:3897

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily, and OmpR/PhoB-type DNA-binding domain

8 of 30

2.13

5.31

4.33e-13

CL:3901

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain, and PAS fold-3

4 of 11

2.27

2.91

1.75e-06

CL:3903

PAS fold, and PAS fold-4

3 of 5

2.48

2.32

4.49e-05

CL:3923

Mixed, incl. Peptidyl-aspartic acid modification, and Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

3 of 7

2.34

2.14

8.64e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

lagg02020

Two-component system

6 of 141

1.33

1.55

1.50e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

8 of 72

1.75

3.6

4.49e-11

KW-0418

Kinase

5 of 115

1.34

1.33

0.00020

KW-0808

Transferase

6 of 620

0.69

0.4

0.0413

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 34

2.02

4.19

1.48e-10

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

7 of 36

1.99

4.13

1.48e-10

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

7 of 38

1.97

4.07

1.58e-10

IPR005467

Histidine kinase domain

7 of 39

1.96

4.04

1.58e-10

IPR003594

Histidine kinase/HSP90-like ATPase

7 of 42

1.93

3.93

2.13e-10

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

7 of 39

1.96

4.23

3.66e-11

SM00387

Histidine kinase-like ATPases

7 of 44

1.91

4.05

5.27e-11

SM00448

cheY-homologous receiver domain

8 of 67

1.78

3.8

1.64e-11

SM00091

PAS domain

4 of 33

1.79

2.11

1.86e-05

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

2 of 23

1.64

0.77

0.0295

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