STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
A0A1Y1VRE9Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)    
Predicted Functional Partners:
A0A1Y1VWU0
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
 
 
 0.987
A0A1Y1WZ61
3-hydroxy-3-methylglutaryl coenzyme A reductase.
 
 0.944
A0A1Y1XHK1
O-acetylhomoserine ami.
 
      0.888
A0A1Y1X1L0
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.870
A0A1Y1XMM7
Uncharacterized protein.
  
 
 0.870
A0A1Y1WUI1
Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
   
 
 0.851
A0A1Y1XDT0
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.851
A0A1Y1XCR9
DUF500-domain-containing protein.
    
   0.848
A0A1Y1X539
Uncharacterized protein.
  
 0.843
A0A1Y1WVJ0
O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
      0.828
Your Current Organism:
Anaeromyces robustus
NCBI taxonomy Id: 1754192
Other names: A. robustus, Anaeromyces sp. KS-2015, Anaeromyces sp. S4, JMRC:SF:12178, S4
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