STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1X7A0Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (497 aa)    
Predicted Functional Partners:
A0A1Y1XRB8
Dihydropteroate synthase.
 
 
 0.991
A0A1Y1XM06
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.842
A0A1Y1XDY4
Thymidylate synthase.
     
 0.838
A0A1Y1X585
FTHFS-domain-containing protein.
  
 
 0.829
A0A1Y1XLN3
Anthranilate synthase component I.
  
 
 0.789
A0A1Y1WP51
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.784
A0A1Y1XDA9
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.784
A0A1Y1WZN9
DAO-domain-containing protein.
    
 0.779
A0A1Y1XG36
Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
  
  
0.773
A0A1Y1X0G8
Branched chain amino acid aminotransferase apoenzyme.
    
 0.742
Your Current Organism:
Anaeromyces robustus
NCBI taxonomy Id: 1754192
Other names: A. robustus, Anaeromyces sp. KS-2015, Anaeromyces sp. S4, JMRC:SF:12178, S4
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