STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y1XR84Guanylate cyclase domain-containing protein. (1055 aa)    
Predicted Functional Partners:
A0A1Y1XNY1
Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.803
A0A1Y1WDT7
HD-domain/PDEase-like protein; Belongs to the cyclic nucleotide phosphodiesterase family.
    
 0.775
A0A1Y1WW73
Uncharacterized protein.
     
 0.770
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.762
A0A1Y1XIS0
Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.762
A0A1Y1XJS7
P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the adenylate kinase family.
     
 0.762
A0A1Y1WX48
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.760
A0A1Y1XJH1
Adenosine kinase.
     
 0.732
A0A1Y1X728
HD-domain/PDEase-like protein; Belongs to the cyclic nucleotide phosphodiesterase family.
    
 0.729
A0A1Y1XCP2
Guanylate kinase-like domain-containing protein.
    
 0.720
Your Current Organism:
Anaeromyces robustus
NCBI taxonomy Id: 1754192
Other names: A. robustus, Anaeromyces sp. KS-2015, Anaeromyces sp. S4, JMRC:SF:12178, S4
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