STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (446 aa)    
Predicted Functional Partners:
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
 
 0.997
SSIN_0054
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.924
SSIN_0051
Octaprenyl-diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase (farnesyldiphosphate synthase); Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.914
SSIN_0052
RNA binding methyltransferase FtsJ like.
 
    0.831
argR
Arginine repressor; Regulates arginine biosynthesis genes.
       0.797
SSIN_0055
Serine/threonine protein phosphatase.
  
    0.681
SSIN_0580
Single-stranded-DNA-specific exonuclease RecJ.
  
  
 0.677
SSIN_1363
Pyrimidine-nucleoside phosphorylase.
    
  0.545
nnrD
NAD(P)HX dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
  
    0.529
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.515
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.