Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSIN_1007Catabolite control protein A. (334 aa)    
Predicted Functional Partners:
SSIN_0491
PTS system, maltose and glucose-specific IIB component; PTS system, maltose and glucose-specific IIA component.
   
 
 0.893
SSIN_0122
Phosphocarrier protein of PTS system.
   
 
 0.815
SSIN_1728
PTS system, sucrose-specific IIC component; PTS system, sucrose-specific IIA component.
   
 
 0.813
SSIN_1748
PTS system, beta-glucoside-specific IIC component; PTS system, beta-glucoside-specific IIA component.
   
 
 0.813
SSIN_1935
PTS system, trehalose-specific IIC component.
   
 
 0.813
SSIN_1008
Proline dipeptidase.
  
 
 0.783
codY
GTP-sensing transcriptional pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
    
 
 0.771
SSIN_1379
Cytoplasmic alpha-amylase.
  
 
 0.767
hprK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
  
   
 0.678
SSIN_1005
Glycosyltransferase LafA, responsible for the formation of Glc-DAG.
       0.643
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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