Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSIN_1237Hypothetical protein; FIG01116082. (85 aa)    
Predicted Functional Partners:
SSIN_1235
Putative amino acid ligase found clustered with an amidotransferase.
       0.820
SSIN_1236
Putative amidotransferase; Similar to cobyric acid synthase.
       0.820
SSIN_0274
CBS domain protein; Lmo1865 like protein.
  
  
  0.685
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.659
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
  
  
  0.557
SSIN_1233
Putative secreted protein, YBBR Bacillus subtilis homolog.
       0.550
dacA
YbbP protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.550
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.484
SSIN_1766
Hypothetical protein.
     
  0.484
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
       0.471
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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