Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SSIN_1925TPR-repeat-containing protein. (409 aa)    
Predicted Functional Partners:
SSIN_1924
Hypothetical protein.
       0.855
SSIN_1467
Adenine-specific methyltransferase.
  
     0.770
SSIN_1423
ABC transporter, permease protein EscB.
  
     0.759
divIB
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
     0.756
SSIN_1624
Hypothetical protein; FIG005686; Belongs to the UPF0398 family.
  
     0.751
SSIN_0650
Lipoteichoic acid synthase LtaS Type IIc.
  
     0.738
SSIN_0102
Competence protein CoiA.
  
     0.725
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.717
prsA
Putative parvulin type peptidyl-prolyl isomerase, similarity with PrsA foldase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
 
     0.660
mecA
Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
     0.581
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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