STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (339 aa)    
Predicted Functional Partners:
SSIN_1999
Diphosphomevalonate decarboxylase.
 
  
 0.998
SSIN_1998
Phosphomevalonate kinase.
 
 0.992
SSIN_2000
Mevalonate kinase.
 
  
 0.989
SSIN_1995
Hydroxymethylglutaryl-CoA synthase.
 
 
 0.949
SSIN_0051
Octaprenyl-diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase (farnesyldiphosphate synthase); Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.940
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.919
SSIN_1996
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
   
 0.916
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.814
SSIN_2002
C3-degrading proteinase.
    
  0.811
SSIN_0283
Dihydrolipoamide dehydrogenase of acetoin dehydrogenase.
     
 0.793
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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